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Background Fibrosing mediastinitis (FM), also called sclerosing mediastinitis or mediastinal fibrosis, is a rare disease characterized by excessive fibrotic reaction in the mediastinum and may compromise the airway, the great vessels and other mediastinal structures, with a morbidity directly related to the location and extent of fibrosis. Mediastinitis should be considered in any oropharyngeal infection or esophageal perforation and ruled-out based on imaging. Chronic mediastinitis shares common symptoms with idiopathic retroperitoneal fibrosis. What laboratory studies should you order and what should you expect to find? Results consistent with the diagnosis. Acute mediastinitis Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (601K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References. 786 787 Images in this article Fig 1 on p.787 Fig 2 on p.787 Background: Fibrosing mediastinitis (FM) is an idiosyncratic reaction to infection with Histoplasma capsulatum with where H. capsulatum is endemic suggests that an abnormal immunological host response may be responsible for the development of fibrosis. Our group previously reported an association between subjects with PHFM and human A case of pulmonary hypertension secondary to a compression of a main pulmonary artery by fibrosing mediastinitis which was confirmed by a biopsy with a thoracotomy and chest CT scan and 2D echocardiography performed before and after a trial of steroid therapy demonstrated improvement after steroid therapy. 3 Idiopathic fibrosing mediastinitis is, an uncommon cause of pulmonary hypertension Download reference work entry PDF Definition Mediastinitis can be divided into acute and chronic or fibrosing mediastinitis. Acute mediastinitis usually is bacterial and most commonly results from esophageal perforation. Chronic mediastinitis typically is fungal or tuberculous infection. Abstract A rare case of coexisting retroperitoneal and mediastinal fibrosis is reported. Increasing awareness of this association may lead to earlier recognition of significant symptoms and more effective therapy. Full text Full text is available as a scanned copy of the original print version. Findings suggesting that retroperitoneal fibrosis, mediastinal fibrosis, sclerosing cholangitis, Riedel's thyroiditis, and pseudotumor of the orbit may be different manifestations of a single disease. Ann Intern Med. 1967 May;66(5):884-892. [Abstract] [Google Scholar] Cheris DN, Dadey JL. Fibrosing mediastinitis. An unusual cause for cor pulmonale. General Discussion. Fibrosing mediastinitis (FM) is a rare disease characterized by dense invasive fibrotic infiltration of the mediastinum (middle portion of the chest, situated between the lungs) and/or hilar regions (areas between the upper and lower lobes of each lung) of the chest causing narrowing or occlusion of important chest Discussion. Fibrosing mediastinitis is a rare benign disorder characterized by slowly progressive proliferation of de

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