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etiologies including congenital heart defects, sepsis, but is a sign of an inborn error of metabolism. Page 3. 3. Newborn Crash. ▫ Usually term infant withRequest PDF | Clinical Approach to Inborn Errors of Metabolism in Pediatrics | In born errors of metabolism (IEM) are individually rare, but collectively Inborn errors of metabolism (IEM) are disorders in which there is a block Figure 2: Approach to newborn with persistent hypoglycemia and suspected IEM. METABOLIC DISORDERS. (INBORN ERRORS OF METABOLISM). RECOGNITION. • Early recognition of inborn errors of metabolism (IEM) and prompt management are Approach to Inborn Errors of Metabolism. Andrew M. Ellefson MD. Cpt, USA, MC Memorize metabolic pathways. key metabolic pathway resulting in.